Below are five more sneak previews of Thursday's episode, "Wish You Were Here."

As seen in our first sneak peek, a serial killer, played by Eric Stoltz, is transported to the hospital. Bailey is thrown off by a new doctor, Arizona Robbins (Jessica Capshaw), and Mark laments his recent romantic woes to Callie. He's determined not to sleep with Lexie again, but he definitely adores her. Finally, Izzie tells Alex about Denny ... with surprising results.

Here's a great clip of Mark and Callie discussing their respective love lives ...

Wish You Were Here Sneak Preview #2

Funny stuff. Follow the jump for four more video clips from this week's long-awaited (and hopefully promising) episode of Grey's Anatomy, the first of 2009 ...

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So strong was the speculation that T.R. Knight wanted off Grey's Anatomy - and would be granted this request - that we went so far as to post our favorite memories of George.

But did everybody jump the gun on the actor's departure, only to see cooler heads prevail? Check out this little item from E! Online's spoiler Q&A session yesterday evening ...

Q: What is the big scoop on Grey's Anatomy?

A: I can tell you T.R. Knight's rumored departure is not a done deal and that last I heard from my sources, there is a possibility they may work it out to have him stay on the series. Anyone else crossing your fingers that he'll stick around?

No big news here - but that doesn't make it any less noteworthy. When Grey's Anatomy star Patrick Dempsey is spotted hopping on a flight in Los Angeles, we'll be there to bring it to you. He and the rest of the cast (finally) will be back with a new episode Thursday!

Here's a sneak preview of "Wish You Were Here," next week's all-new episode of Grey's Anatomy. Looks like 2009 is off to an intense start as Derek, Owen, Meredith and Cristina must treat a killer (guest star Eric Stoltz) - and debate the ethics of how to proceed. Take a look ...

Wish You Were Here: Sneak Preview #1

Welcome to the 139th edition of the Grey's Anatomy Insider Caption Contest!

To see who won last week's contest and see all the entries sent in, click here.

Then get ready for an all-new Caption Contest below! To play, just examine this Grey's Anatomy photo, click "comments" and post your best caption(s)!

Grey's Anatomy star Katherine Heigl and Gerard Butler keep close in this new movie still from their upcoming romantic comedy The Ugly Truth, to be released April 3.

In the movie, a romantically challenged morning-show producer (Katherine Heigl) is embroiled in a series of outrageous tests by her male chauvinist correspondent (Gerard Butler), in order to prove his theories on relationships and allow her to find love.

His clever ploys, however lead to an unexpected (yet totally expected) result.

Just one more week until Grey's Anatomy returns with new episodes. Tonight, on this first day of 2009, ABC will be airing "Life During Wartime" at 9 p.m. Here's our episode recap.

A gallery photos, some videos from the episode section contain some cool shots and scenes, while our page dedicated to the episode's music and directory of Grey's Anatomy quotes (of every episode) should help you find the song or the line that you loved.

Our Round Table discussion is always good for a read, and to sound off on any Grey's Anatomy topic, episode, character or story line, feel free to post in our forum!

All of us at Grey's Anatomy Insider would like to wish our readers a healthy and Happy New Year! Thank you all for visiting us so often and making this site so successful.

We know it's been a tough year at times, with plenty of controversial characters, relationships and Grey's Anatomy story lines - and even a writers' strike for good measure.

But in Grey's Anatomy and in life, there is always a time for for new beginnings. Our resolution is to bring you thorough Grey's Anatomy coverage and make this the web's #1 fan community for a show we still love dearly. Here's wishing you all the best in 2009.

Here's hoping for more of this (and other things) come January ...

Nothing particularly new or groundbreaking here, but in case you haven't seen or heard, and want a general idea of what we can expect in the first three episodes of the new year, we've posted ABC's official press releases about them for you below.

With titles like "Wish You Were Here," "Sympathy For the Devil," and "Stairway to Heaven," it looks like the writers are planning something big. Or listening to a lot of classic rock.

We're also compiling promotional photos for "Sympathy for the Devil" and "Stairway to Heaven," which we will be posting soon. Follow the jump for the episode synopses ...

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Patrick Dempsey has announced plans for a 100-mile bike trek fundraiser for the cancer center that bears his name at Central Maine Medical Center.

The Grey's Anatomy star, a Maine native who plays the hunky neurosurgeon known as Dr. Derek Shepherd, a.k.a. McDreamy, on ABC's medical drama, was in his native Lewiston, Maine, on Monday to promote the bike ride and 5-kilometer walk/run planned for October.

The event will benefit the Patrick Dempsey Center for Cancer Hope & Healing, which opened last spring. The actor has provided a $250,000 donation to the center.

Dempsey was born in Lewiston and grew up in the Turner-Buckfield area. He currently owns a home in Harpswell, on the state's coast, where his mom also lives.

Grey's Anatomy's Patrick Dempsey is an avid cyclist and auto racer.